Error: "SendPipeCommand: Cannot access a closed pipe." when I set Outlook Synchronisation Preferences in Act! v20.1

Symptom: When I try to set Outlook synchronisation preferences with Outlook 2016 in Act! v20.1 on Windows 10, I receive the Error: "SendPipeCommand: Cannot access a closed pipe."

Product Details: 
Product Family: Act!
Product: Act! Pro, Act! Premium, Act! Premium (access via web)
Version: v20.1

Environment:
OS: Windows 10
Third Party: Microsoft Outlook 2016

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Cause:
The cause is not currently known.

Solution:

You may be able to resolve this issue by following the steps below:

1. Depending on what deployment (type of installation) you’re trying to configure Outlook synchronization with, browse to one of the following locations:
   
   • Act! Pro/Act! Premium: C:\Program Files (x86)\ACT\ACT For Windows
     
   • Act! Premium (access via web) (from the web server): C:\Program Files (x86)\ACT\ACT For Windows
     
   • Act! Premium (access via web) or Act! Premium Cloud: C:\Program Files (x86)\ACT\ACT for Web\ClientSrvs\Office\Outlook
     
   
   
2. Locate and right-click Act!.Integration.exe, then choose Properties
   
3. Click the Compatibility tab
   
4. Enable the option to “Run this program in compatibility mode for:”
   
5. Compatibility mode drop-down, choose Windows 8
   
6. Click OK
   
7. Attempt to configure your Outlook synchronization preferences to test